MLN 8237


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83 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 3
2 ATP binding cassette subfamily C member 1 MRP1_HUMAN ABCC1 Homo sapiens 4363 1125 1
3 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 1
4 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 1
5 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 9
6 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 1
7 aquaporin 2 AQP2_RAT Aqp2 Rattus norvegicus 25386 198 1
8 androgen receptor ANDR_HUMAN AR Homo sapiens 367 1832 1
9 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 1
10 aurora kinase A AURKA_MOUSE Aurka Mus musculus 20878 82 15
11 aurora kinase A AURKA_HUMAN AURKA Homo sapiens 6790 433 110
12 aurora kinase B AURKB_HUMAN AURKB Homo sapiens 9212 244 1
13 B cell leukemia/lymphoma 2 BCL2_MOUSE Bcl2 Mus musculus 12043 1497 1
14 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 2
15 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 1
16 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 2
17 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 1
18 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 1
19 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
20 CD274 antigen PD1L1_MOUSE Cd274 Mus musculus 60533 466 1
21 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 1
22 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 1
23 CD38 molecule CD38_HUMAN CD38 Homo sapiens 952 501 1
24 CD8a molecule CD8A_HUMAN CD8A Homo sapiens 925 1925 1
25 cell division cycle 20 CDC20_MOUSE Cdc20 Mus musculus 107995 16 1
26 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 1
27 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 1
28 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 1
29 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 1
30 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 1
31 cytochrome P450 family 2 subfamily C member 19 CP2CJ_HUMAN CYP2C19 Homo sapiens 1557 1098 1
32 cytochrome P450 family 2 subfamily C member 8 CP2C8_HUMAN CYP2C8 Homo sapiens 1558 590 1
33 cytochrome P450 family 2 subfamily C member 9 CP2C9_HUMAN CYP2C9 Homo sapiens 1559 1244 1
34 cytochrome P450 family 2 subfamily D member 6 CP2D6_HUMAN CYP2D6 Homo sapiens 1565 1531 1
35 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 3
36 DNA methyltransferase 1 DNMT1_HUMAN DNMT1 Homo sapiens 1786 621 1
37 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 1
38 eukaryotic translation initiation factor 4E IF4E_MOUSE Eif4e Mus musculus 13684 78 1
39 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 1
40 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 1
41 enhancer of zeste 2 polycomb repressive complex 2 subunit EZH2_HUMAN EZH2 Homo sapiens 2146 470 2
42 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 1
43 GLI family zinc finger 2 GLI2_HUMAN GLI2 Homo sapiens 2736 1670 1
44 glycogen synthase kinase 3 beta GSK3B_HUMAN GSK3B Homo sapiens 2932 1189 1
45 histone H3 associated protein kinase HASP_MOUSE Haspin Mus musculus 14841 11 1
46 histone deacetylase 6 HDAC6_HUMAN HDAC6 Homo sapiens 10013 454 1
47 interferon alpha inducible protein 27 IFI27_HUMAN IFI27 Homo sapiens 3429 662 1
48 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 1
49 lysine demethylase 1A KDM1A_HUMAN KDM1A Homo sapiens 23028 403 1
50 lysine demethylase 6B KDM6B_HUMAN KDM6B Homo sapiens 23135 93 1